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Infertility Research
Herbal remedies may affect
sperm motility
Commonly used herbal remedies can interfere with
sperm motility and many should be avoided by couples experiencing
fertility problems, according to a report from the Department of
Gynecology and Obstetrics, Loma Linda University School of Medicine,
California 92350, USA.
Researchers analyzed sperm motility parameters in
the presence of herbs. Washed sperm were incubated in either saw-palmetto
(Serenoa repens, Permixon Sabal serrulatum), echinacea purpura, ginkgo
biloba, St. John's wort (Hypericum perforatum), or control medium.
Parameters were measured on a Hamilton-Thorn analyzer after 1, 4, 24, and
48 hr at 37 degrees C.
The results showed that sperm motility was
inhibited at the high concentration (0.6 mg/mL) of St. John's wort.
Curvilinear velocities and beat cross frequencies also decreased, but not
hyperactivation.
High-concentration saw-palmetto, echinacea, or ginkgo inhibited motility
within 24 and 48 hours.
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The report concludes that a potent inhibition of
sperm motility was seen in St. John's wort unrelated to changes in pH.
Furthermore, sperm viability was compromised in St. John's wort,
suggesting a spermicidal
effect. Metabolic changes were observed in saw-palmetto-treated sperm.
High-concentration echinacea purpura also interfered with sperm enzymes.
It is therefore recommended that couples
experiencing fertility problems and those planning a family should avoid
taking these herbal remedies, especially in high dosages.
Inhibition of human sperm
motility by specific herbs used in alternative medicine.Ondrizek RR; Chan PJ; Patton WC; King A. J Assist Reprod Genet, 16:87-91,
1999 Feb
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The Internet Health Library 2000
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